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Am J Physiol Endocrinol Metab 2000;279:E501E507

Conventional thinking posits that a primary defect in adaptive immunity promotes recruitment and entry of peripherally activated lymphocytes into the CNS across a disrupted bloodbrain barrier where a complex cascade of autoimmune/inflammatory processes culminates in edema, and destruction of myelin, axons and oligodendrocytes (for detailed reviews see Dendrou et al., 2015

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PMID: 3575154

2d-f) and weighted (Supplementary Fig

The reason there are so few side effects is that the amino acids can disassociate after doing its job, rather than having to be metabolized by the liver or the kidneys